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Descriptions are generated automatically from the ICTVdB database including links. Some descriptions are only very basic and links may point to documents that are not yet published on the Web.

03.019.0.01.014.00.213.001. SARS coronavirus, isolate SPB200300592

Cite this publication as: ICTVdB Management (2006). 03.019.0.01.014.00.213.001. SARS coronavirus, isolate SPB200300592. In: ICTVdB - The Universal Virus Database, version 4. Büchen-Osmond, C. (Ed), Columbia University, New York, USA

Cite this site as: ICTVdB - The Universal Virus Database, version 4. http://www.ncbi.nlm.nih.gov/ICTVdb/ICTVdB/

Table of Contents

Isolate Description

Isolate designation: SPB200300592 (Urbani).
Isolation date: 21 June 2003.
Location: Bangkok; Thailand.

Host of Isolate and Habitat Details
Source of isolate: human.

Collection and Isolation Details
Virus was isolated by Dr Thomas Ksiazek. Special Pathogens Branch; Centers for Disease Control and Prevention; 1600 Clifton Road; Atlanta; Georgia; 30333; the United States of America; email: [mailto] tgk0@cdc.gov.

Reference to Isolation Report
Ksiazek, T.G., Erdman, D., Goldsmith, C.S., Zaki, S.R. et al. (2003) A novel coronavirus associated with severe respiratory syndrome. N. Engl. J. Med., 248:1953-1966.

Depositories and Collections

The isolate is available at an institution at Special Pathogens Branch, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333.

Biocontainment Level

Distribution of this virus falls under quarantine restrictions. It is recommended to handle this virus at the biocontainment level BSL-3 (WHO for live virus), or recommended to handle this virus at the biocontainment level BSL-4 (For animal infection).

Classification

This is a description of a vertebrate virus at the isolate level.

ICTVdB Virus Code: 03.019.0.01.014.00.213.001. Virus accession number: 19114592.

Name, Synonyms and Lineage

Virus is assigned to species SARS coronavirus of the genus 03.019.0.01. Coronavirus; of the family 03.019. Coronaviridae; of the order 03. Nidovirales .

Nucleic Acid

The genome is monomeric; not segmented and contains a single molecule of linear, positive-sense, single-stranded RNA. Sequence can be accessed from GenBank (AY278741, the RNA-1 is fully sequenced, complete sequence is 29727 nucleotides long. Reference to nucleotide sequence Rota, P.A., Oberste, M.S., Monroe, S.S., Nix, W.A. et al. (2003) Characterization of a novel coronavirus associated with severe acute respiratory syndrome. Science, 300: 1394-1399.

Biological Properties

Natural Host

Domain
Viral hosts belong to the Domain Eucarya.

Domain Eucarya
Kingdom Animalia.

Kingdom Animalia
Phylum Chordata.

Phylum Vertebrata Class Mammalia.

Class Mammalia Order Primates.

Diagnostic Hosts

For virus isolation the most commonly used cell lines or tissue cultures are Vero E6. Virus has been propagated in cell culture.

Comments

This description has been compiled from data presented in the literature.

References

Ksiazek, T.G., Erdman, D., Goldsmith, C.S., Zaki, S.R., et al., (2003). A novel coronavirus associated with severe respiratory syndrome, N Engl J Med, 348, 1953-1966.

Rota, P.A., Oberste, M.S., Monroe, S.S., Nix, W.A. et al. (2003) Characterization of a novel coronavirus associated with severe acute respiratory syndrome. Science, 300, 1394-1399.

Contributor

Data have been submitted online to ICTVdB by
Antony J. Della-Porta;
Biosecurity and Biocontainment;
International Consultants;
PO Box 531;
Geelong; Victoria; 3220;
Australia;
Tel: + +61 3 5243 0433;
Fax: + +61 3 5243 0052;
email: [mailto] tony.dellaporta@bigpond.com. Involved in the isolation of the virus was also Dr. Paul Rota; Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, Georgia 30333, United States of America par1@cdc.gov; Dr. Dean Erdman; Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, Georgia 30333, United States of America; Ms. Cynthia Goldsmith; Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, Georgia 30333, United States of America.

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The description has been generated automatically from DELTA files.

ICTVdB - The Universal Virus Database, developed for the International Committee on Taxonomy of Viruses (ICTV) by Dr Cornelia Büchen-Osmond, is written in DELTA. The virus descriptions in ICTVdB are coded by ICTV members and experts, or by the ICTVdB Management using data provided by the experts, the literature or the latest ICTV Report. The character list is the underlying code. All virus descriptions are based on the character list and natural language translations from the encoded descriptions are automatically generated and formatted for display on the Web.

Developer of the DELTA software: M. J. Dallwitz, T. Paine and E. Zurcher
ICTVdB and DELTA related References

Comments to ICTVdB Management
Last updated on 25 April 2006 by Cornelia Büchen-Osmond
Copyright © 2002 International Committee on Taxonomy of Viruses. All rights reserved.

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