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03.019.0.01.014.00.044.003. SARS-Coronavirus AS

Cite this publication as: ICTVdB Management (2006). 03.019.0.01.014.00.044.003. SARS-Coronavirus AS. In: ICTVdB - The Universal Virus Database, version 4. Büchen-Osmond, C. (Ed), Columbia University, New York, USA

Cite this site as: ICTVdB - The Universal Virus Database, version 4. http://www.ncbi.nlm.nih.gov/ICTVdb/ICTVdB/

Table of Contents

Isolate Description

Isolate designation: AS.
Isolation date: 03 June 2003.
Location: China.

Host of Isolate and Habitat Details
Source of isolate: human.
Virus was isolated from sputum sample.
Virus was isolated from an adult.

Collection and Isolation Details
Virus was isolated by Prof Claudia Balotta. Institute of Infectious and Tropical Diseases, L. Sacco Hospital; University of Milan; Via G.B. Grassi 74; Milan; 20157; Italy; email: [mailto] claudia.balotta@unimi.it.

Reference to Isolation Report
unpublished.

Depositories and Collections

The isolate is unavailable.

Classification

This is a description of a vertebrate virus at the isolate level.

ICTVdB Virus Code: 03.019.0.01.014.00.044.003. Virus accession number: I001SARS. Former accession number: 41C72D46.
NCBI Taxon Identifier NCBI Taxonomy ID: 248485.

Name, Synonyms and Lineage

Virus is assigned to species SARS coronavirus of the genus 03.019.0.01. Coronavirus; of the family 03.019. Coronaviridae; of the order 03. Nidovirales .

Nucleic Acid

The genome is not segmented and contains a single molecule of linear positive-sense, single-stranded RNA. The complete genome is 29711 nucleotides long. Sequence can be accessed from GenBank; the RNA is fully sequenced, complete sequence is 29711 nucleotides long and encodes The genome has been found to encode open reading frames (orf3a, orf3b, orf6, orf7a, orf7b, orf8a, orf8b, orf9b), spike protein, nucleocapsid, envelope, membrane. Sequence has the accession number [AY427439].

GenBank records for nucleotide sequences; complete genome sequences.

Biological Properties

Natural Host

Domain
Viral hosts belong to the Domain Eucarya.

Domain Eucarya
Kingdom Animalia.

Kingdom Animalia
Phylum Chordata.

Phylum Vertebrata
Subphylum Vertebrata; Class Mammalia.

Class Mammalia Order Primates;
Family Hominidae.
Virus infects Homo sapiens (human).

General Symptoms in Animals Infection can affect the respiratory system. Signs and symptoms include dyspnoea or wheezing (positive chest radiograph).

Severity and Occurrence of Disease

Host: Infection is apparent. The infection is clinically expressed.

Comments

Dr. Corvasce, who participated in the sequencing of SARS-CoV AS, does not consider it an isolate but rather a primary sample. However, half of the sputum sample.

References

PubMed References.

Contributor

Data have been submitted online to ICTVdB on 01-12-05 by
Sara Mullins
American Type Culture Collection;
George Mason University;
PW II, 10801 University Boulevard;
Manassas; VA; 20110;
United States of America;
Tel: + 703-365-2700;
Fax: + 703-365-2701;
email: ICTVdB Management. Involved in the isolation of the virus was also Prof. Stefano Corvasce; Institute of Infectious and Tropical Diseases, L. Sacco Hospital, University of Milan, Milan, Italy. stefano.corvasce@unimi.it; Prof. Michela Barbara Violin; Institute of Infectious and Tropical Diseases, L. Sacco Hospital, University of Milan, Milan, Italy. michela.violin@unimi.it; Prof. Massimo Galli; Institute of Infectious and Tropical Diseases, L. Sacco Hospital, University of Milan, Milan, Italy. massimo.galli@unimi.it.



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DELTA - DEscription Language for TAxonomy developed by Dr Mike Dallwitz, Toni Paine and Eric Zurcher, CSIRO Entomology, Canberra, Australia. ICTVdB - The Universal Virus Database, developed for the International Committee on Taxonomy of Viruses by Dr Cornelia Büchen-Osmond is written in DELTA. The virus descriptions in ICTVdB are coded by, or using data from experts in the field of virology or members ICTV. The character list is the underlying code. All virus descriptions are based on the character list and natural language translations are automatically generated and formatted for display on the Web from the descriptions in DELTA-format. The description has been generated automatically from DELTA files. DELTA - DEscription Language for TAxonomy developed by Dr Mike Dallwitz, Toni Paine and Eric Zurcher, CSIRO Entomology, Canberra, Australia.

ICTVdB - The Universal Virus Database, developed for the International Committee on Taxonomy of Viruses (ICTV) by Dr Cornelia Büchen-Osmond, is written in DELTA. The virus descriptions in ICTVdB are coded by ICTV members and experts, or by the ICTVdB Management using data provided by the experts, the literature or the latest ICTV Report. The character list is the underlying code. All virus descriptions are based on the character list and natural language translations from the encoded descriptions are automatically generated and formatted for display on the Web.

Developer of the DELTA software: M. J. Dallwitz, T. Paine and E. Zurcher

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Last updated on 25 April 2006 by Cornelia Büchen-Osmond
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