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generated automatically from the ICTVdB database including links. Some
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00.060. Reoviridae
Cite this publication as: ICTVdB Management (2006). 00.060. Reoviridae.
In: ICTVdB - The Universal Virus Database, version 4. Büchen-Osmond,
C. (Ed), Columbia University, New York, USA
Cite this site as: ICTVdB
- The Universal Virus Database, version 4.
http://www.ncbi.nlm.nih.gov/ICTVdb/ICTVdB/
This is a description of an
invertebrate, plant and vertebrate virus at the
family level.
ICTVdB Virus Code: 00.060. Virus accession number: 00060FAM.
Obsolete virus code: 60.; superceded accession number: 60000000.
NCBI Taxon Identifier NCBI Taxonomy ID:
10880.
Virions consist of a capsid, a core, and a nucleoprotein
complex. During their life cycle, virions loose during the extracellular phase
the sometimes observed intracellular envelope. Virus may be sequestered within
inclusion bodies that are not occluded and typically contain one
nucleocapsid, or occluded by protein bodies (in the case of Cypovirus).
Virus initiating infection is occluded by a crystalline protein matrix of
polyhedral shape. Each occlusion body contains several virions. Virus
capsid is usually not enveloped, or enveloped when
immature particles are budding into the endoplasmatic reticulum acquiring a
transient lipid envelope before leaving the infected cell. Capsid/nucleocapsid
is round and exhibits icosahedral symmetry. The capsid
is isometric and has a diameter of 60-80 nm. The capsid
shells of virions are composed of two layers, or three layers. All shells are
usually present, or the outer shell is often lost during preparation. Capsids
appear round. The capsid surface structure reveals a regular pattern with
distinctive features is smooth, or appears rough. The capsomer
arrangement is clearly visible. Surface projections are often lost during
preparation, or not present, or distinct spikes protruding from the 12
vertices. Virus preparations contain one particle component.
Only one species is recovered in preparations. Incomplete
particles are common. They are devoid of nucleic acid characterized by capsids
with dark centers in negative stain preparations, or incompletely assembled
capsids.
Virions have a buoyant density in CsCl of 1.26-1.44 g
cm-3.
The Mr
of the genome constitutes 15-20% of the virion by weight. The genome is
monomeric; segmented and consists of ten segments of to twelve segments, depending on genus, of
linear, double-stranded RNA. The
complete genome is 18200-30500 nucleotides long. The 5'-end of the genome
has a methylated nucleotide cap (on the positive strand of each duplex, the
negative strands have a phosphorylated terminus, cap sequence type is
m7G5ppp5'GmpNp. The multipartite genome is found in one type of particle only.
Each virion contains a single copy of the genome; a full length copy.
GenBank records for
nucleotide sequences;
complete genome sequences.
Proteins
constitute about 80-85% of the particle weight.
The viral genome encodes structural proteins and non-structural proteins.
Lipids are
usually absent, or present during morphogenesis in minute amounts
as myristic acid residues (covalently attached to one of the virion
proteins) and are located in the envelope (in an intermediate stage
that is subsequently removed).
Natural Host
Virus infects during its life cycle arthropod and vertebrate hosts, or a single
type of vertebrate host. Domain Viral hosts
belong to the Domain Eucarya.
Domain Eucarya
Kingdom Animalia.
Kingdom Animalia
Phylum Chordata.
Phylum Vertebrata
Subphylum Vertebrata.
Class Aves and Mammalia.
Class Mammalia Order Primates, Perissodactyla,
and Artiodactyla;
Family Hominidae.
Virus infects Homo sapiens
(human).
Virus is transmitted by a vector, or not transmitted by a
vector.
00.060.0.01.
Orthoreovirus
00.060.0.02.
Orbivirus
00.060.0.03.
Rotavirus
00.060.0.04.
Coltivirus
00.060.0.05.
Aquareovirus
00.060.0.06.
Cypovirus
00.060.0.07.
Fijivirus
00.060.0.08.
Phytoreovirus
00.060.0.09.
Oryzavirus.
Data Sources and
Contributions
The
following generic references are cited in the most recent ICTV Report.
PubMed References.
Taxon images: • EM by Cornelia Büchen-Osmond.
• EM from Stewart McNulty,
Queens University, Belfast. • EM from Stewart McNulty, Queens University,
Belfast.
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