Descriptions are
generated automatically from the ICTVdB database including links. Some
descriptions are only very basic and links may point to documents that are not
yet published on the Web.
00.031.3.02. Rhadinovirus
Cite this publication as: ICTVdB Management (2006).
00.031.3.02. Rhadinovirus. In: ICTVdB - The Universal Virus Database,
version 4. Büchen-Osmond, C. (Ed), Columbia University, New York, USA
Cite this site as: ICTVdB - The Universal Virus Database, version 4.
http://www.ncbi.nlm.nih.gov/ICTVdb/ICTVdB/
This is a description of a
vertebrate virus at the genus level.
ICTVdB Virus Code: 00.031.3.02. Virus accession number:
031302GE. Obsolete virus code: 31.3.2.; superceded accession number: 31320000.
NCBI Taxon Identifier NCBI Taxonomy ID:
10379.
Name, Synonyms and Lineage
Synonym(s): Ateline
herpesvirus group. Virus is of the subfamily
00.031.3.
Gammaherpesvirinae; of the family
00.031.
Herpesviridae.
Virions consist of an envelope, a tegument, a
nucleocapsid, and a core. Virus capsid is enveloped. Virions are spherical to
pleomorphic. Virions measure 150-200 nm in diameter.
Surface projections are densely dispersed, small spikes that cover evenly the surface. Teguments
do not display a structure and proteins in variable amounts
are arranged sometimes in an asymmetric layer located between envelope and capsid.
Capsid/nucleocapsid is round and exhibits icosahedral symmetry
(T=16). The capsid is isometric
and has a diameter of 100-110 nm. Capsids appear hexagonal in outline.
The capsomer arrangement is clearly visible. The capsid consists of 162
capsomers. Surface projections are distinct and consist of a hexagonal
base with a hole running half-way down the long axis. The core consists
of a fibrillar spool on which the DNA is wrapped. The end of the fibers are
anchored to the underside of the capsid shell.
Capsids can be penetrated by stain and some appear dark in the center
(although intact envelope impermeable to stain). Incomplete particles are
common. They are cores lacking capsid shells.
The
genome is not segmented and contains a single molecule of linear
double-stranded DNA. Minor species of non-genomic nucleic
acid are also found in virions. The encapsidated nucleic acid is mainly of
genomic origin, but virions may also contain nucleic acid of host origin, or
subgenomic RNA including M host RNA, host rRNA, and fragments of host
DNA. Genome H is between 1400-56000 nts long. The length depends on the
number of repeat units, virions may contain one subgenomic nucleic acid
species. The complete genome is 145000-165000 nucleotides long, is
sequenced, complete sequence is about
112000 nucleotides long (L-DNA of M genome). The genome has a guanine + cytosine
content of 36 % (L-DNA), or 72 % (H-DNA of the M genome; stretch of quasi unique
sequences low in GC content flanked at both ends with numerous repeat sequences
of high GC content). The genome has terminally redundant sequences. The
terminally redundant sequences have reiterated terminal sequences that are
tandemly repeated (H-DNA, are reiterated, but not repeated internally. The
genome sequence is repeated at both ends. Each virion contains multiple copies
of the genome; 2 copies per particle (genome M and H).
GenBank records for
nucleotide sequences;
complete genome sequences.
The viral
genome encodes structural proteins and non-structural proteins located
in the envelope, capsid, and tegument.
Structural Proteins: Internal lipid membrane consists of
several proteins.
Lipids are
present and located in the envelope. The composition of viral
lipids is not exactly known. The lipids are of host origin
and are derived from nuclear or host cell membranes.
Natural Host
Virus infects during its life cycle a single type of vertebrate host.
Domain
Viral hosts belong to the Domain Eucarya.
Domain Eucarya
Kingdom Animalia.
Kingdom Animalia
Phylum Chordata.
Phylum Vertebrata
Subphylum Vertebrata.
Class Mammalia.
Type species 00.031.3.02.001.
Saimirine herpesvirus 2 .
List of Species in the
Genus.
Data Sources and
Contributions
The
following generic references are cited in the most recent ICTV Report.
PubMed References.
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