Descriptions are
generated automatically from the ICTVdB database including links. Some
descriptions are only very basic and links may point to documents that are not
yet published on the Web.
00.030.0.02.
Avihepadnavirus
Cite this publication as: ICTVdB
Management (2006). 00.030.0.02. Avihepadnavirus. In: ICTVdB - The Universal
Virus Database, version 4. Büchen-Osmond, C. (Ed), Columbia University,
New York, USA
Cite this site as: ICTVdB - The Universal Virus
Database, version 4.
http://www.ncbi.nlm.nih.gov/ICTVdb/ICTVdB/
This is a description of a
vertebrate virus at the genus level.
ICTVdB Virus Code: 00.030.0.02. Virus accession number:
030002GE. Obsolete virus code: 30.0.2.; superceded accession number: 30020000.
NCBI Taxon Identifier NCBI Taxonomy ID:
10437.
Name, Synonyms and Lineage
Synonym(s): Duck
hepatitis B group. Virus is of the family
00.030.
Hepadnaviridae.
Virions consist of an envelope and a nucleocapsid. Virus
capsid is enveloped by a detergent sensitive lipoprotein (7 nm).
Virions are spherical to pleomorphic (at times, filamentous forms occur and
spherical structures that lack cores are common (HBsAg particles). Virions
measure 40-48 nm in diameter, or 22 nm in diameter (for
the HBsAg particles of variable length). The envelope has no surface
projections. Capsid/nucleocapsid is round and exhibits
icosahedral symmetry. The nucleocapsid is isometricand
has a diameter of 35 nm. The capsid surface structure frequently reveals a
regular pattern with distinctive features (concentric rings). The capsid
consists of 180 capsomers.
Incomplete particles are common.
Virions have a buoyant density in CsCl of 1.14-1.16 g
cm-3.
The
genome is not segmented and contains a single molecule of circular. The
genome is -RT. The genome is partially double-stranded DNA
that forms a covalently closed circle (with 5' end of the full length minus
strand which is linked to the viral DNA polymerase). The complete genome is
3020-3320 nucleotides long, or 1700-2800 nucleotides long (for the
full and short length strand, respectively). The genome has a guanine + cytosine
content of 48 %. The genome sequence has termini with cohesive ends (that match
the uniquely located 5'-ends of the two strands which overlap by
approximately 50 nucleotides and maintain the circular configuration of the
DNA). The negative-sense or non-coding strand (complementary to the viral mRNA)
is full-length; positive sense strand (the viral mRNA) is shorter than
full-length. The double stranded genome has a nick at a unique site on
full length negative strand opposite at a position 50 nucleotides
downstream from the 5' end of the positive sense strand. The
5'-end of the negative-sense strand has a covalently attached terminal
protein; positive-sense strand has a 5' capped oligoribonucleotide primer. The
3'-terminus has conserved nucleotide sequences; of 1 nucleotides in length.
GenBank records for
nucleotide sequences;
complete genome sequences.
The viral
genome encodes structural proteins and non-structural proteins located
in the envelope and capsid.
Non-Structural Proteins: The virus codes for an RNA-dependent
DNA polymerase.
Lipids are
present and located in the envelope and empty particles (HBsAG
components). The composition of viral lipids is known. The composition of viral
lipids and host cell membranes are similar. The lipids are derived from a host
membrane compartment intermediate between and are derived from
endoplasmatic reticulum membranes and Golgi membranes. Viral membranes include
phospholipids, cholesterol, cholesterol esters, and triglycerides.
Translation: Replication involves a
reverse transcription step.
Natural Host
Virus infects during its life cycle a single type of vertebrate host.
Domain
Viral hosts belong to the Domain Eucarya.
Domain Eucarya
Kingdom Animalia.
Kingdom Animalia
Phylum Chordata.
Phylum Vertebrata
Subphylum Vertebrata.
Class Aves.
Class Aves Order Anseriformes; virus infects
Anatidae.
Virus infects Anas (duck).
Type species 00.030.0.02.001.
Duck hepatitis B virus .
List of Species in the
Genus.
Data Sources and
Contributions
The
following generic references are cited in the most recent ICTV Report.
PubMed References.
Google Analytics: activity view