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00.011.0.01.003. Akabane virus


Cite this publication as: ICTVdB Management (2006). 00.011.0.01.003. Akabane virus. In: ICTVdB - The Universal Virus Database, version 4. Büchen-Osmond, C. (Ed), Columbia University, New York, USA

Cite this site as: ICTVdB - The Universal Virus Database, version 4. http://www.ncbi.nlm.nih.gov/ICTVdb/ICTVdB/


Table of Contents

Isolate Description

Isolation date: not specified.
Location: not specified.

Host of Isolate and Habitat Details
Source of isolate: mosquitoes, culicoid flies.

Comments on host and host range: Symptomatic infections are seen only in cattle, sheep and goats. Antibodies to the virus have also been found in horses, buffalo, deer, camels and dogs.

Collection and Isolation Details
Virus was isolated by unknown.

Classification

This is a description of an invertebrate and vertebrate virus at the species level.

ICTVdB Virus Code: 00.011.0.01.003. Virus accession number: 11010003.
NCBI Taxon Identifier NCBI Taxonomy ID: 70566.

Name, Synonyms and Lineage

ICTV approved acronym: AKAV. Virus is an ICTV approved species of the genus 00.011.0.01. Orthobunyavirus; of the family 00.011. Bunyaviridae.

Nucleic Acid

The genome is segmented and consists of three segments of linear negative-sense, single-stranded RNA.

GenBank records for nucleotide sequences; complete genome sequences.

Biological Properties

Natural Host

Domain
Viral hosts belong to the Domain Eucarya.

Domain Eucarya
Kingdom Animalia.

Kingdom Animalia
Phylum Arthropoda and Chordata.

Phylum Arthropoda
Subphylum Hexapoda; Class Insecta; Subclass Pterygota (winged insects), Order Diptera.

Phylum Vertebrata
Subphylum Vertebrata; Class Mammalia.

Class Mammalia Order Artiodactyla;
Family Bovidae: Subfamily Bovinae and Caprinae; virus infects Genus Bos taurus (cow, cattle, virus infects Genus Capra and Ovis .

General Symptoms in Animals Infection can affect the nervous system and reproductive system. Signs and symptoms include abortion, fetal damage, malformation, and mummification (Akabane manifests as a seasonal, sporadic epidemic of abortions, stillbirths, premature births and deformed fetuses or neonates in cattle, sheep and goats. The pregnant dam experiences no clinical symptoms at the time of infection. Infection in the first trimester produces foetal damage in utero. Dystocia may occur at parturition due to badly deformed fetuses. Badly deformed fetuses will be dead with limbs locked into flexed or extended position. The mortality rate is very high in affected newborns. Most animals die soon after birth or must be euthanized., deafness, hydrocephaly, microcephaly, paralysis (Live neonates frequently have central nervous system deficiencies manifested clinically as blindness, nystagmus, dullness, slow suckling and incoordination).

Severity and Occurrence of Disease

Host: The disease has the name Congenital Arthrogryposis-Hydranencephaly Syndrome, A-H Syndrome, Akabane Disease.

Transmission and Vector Relationships

Virus is transmitted by a vector. Virus is not transmitted by contact between hosts.

Vector Transmission:
Virus is transmitted by arthropods, by insects of the order Diptera
Aedes vexans, Culex tritaeniorhynchus, C. oxystoma in Japan, Anopheles funestus in Kenya, and Culicoides milnei, C. imicola in Africa. In Australia the main vector appears to be Culicoides brevitarsis. Virus is transmitted congenitally to the progeny of the vector.

Geographical Distribution

The virus is known to occur in subtropical regions and tropical regions (The virus is believed to be distributed through two large north-south geographical bands. Firstly from Japan through South East Asia to Australia, and secondly from the Middle East through Africa to South Africa).

List of Strains and Isolates in the Species

00.011.0.01.003.16.001. OBE-1 strain
00.011.0.01.003.16.002. Jagar-39 strain
00.011.0.01.003.16.003. NT-14 strain
00.011.0.01.003.16.004. PT-17 strain
00.011.0.01.003.16.005. Iriki strain
00.011.0.01.003.16.014. Sabo strain
00.011.0.01.003.16.014.001. Sabo strain, An 9398 isolate
00.011.0.01.003.16.021. Tinaroo strain
00.011.0.01.003.16.021.001. Tinaroo strain, CSIRO153 isolate
00.011.0.01.003.16.024. Yaba-7 strain.

References

The following generic references are cited in the most recent ICTV Report.

PubMed References.




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DELTA - DEscription
Language for TAxonomy developed by Dr Mike Dallwitz, Toni Paine and Eric
Zurcher, CSIRO Entomology, Canberra, Australia. ICTVdB - The Universal Virus
Database, developed for the International Committee on Taxonomy of Viruses by Dr
Cornelia Büchen-Osmond is written in DELTA. The virus descriptions in
ICTVdB are coded by, or using data from experts in the field of virology or
members ICTV. The character list is the underlying code. All virus descriptions
are based on the character list and natural language translations are
automatically generated and formatted for display on the Web from the
descriptions in DELTA-format. The description has been generated automatically from DELTA files. DELTA - DEscription
Language for TAxonomy developed by Dr Mike Dallwitz, Toni Paine and Eric
Zurcher, CSIRO Entomology, Canberra, Australia.

ICTVdB - The Universal Virus Database, developed for the International Committee on Taxonomy of Viruses (ICTV) by Dr Cornelia Büchen-Osmond, is written in DELTA. The virus descriptions in ICTVdB are coded by ICTV members and experts, or by the ICTVdB Management using data provided by the experts, the literature or the latest ICTV Report. The character list is the underlying code. All virus descriptions are based on the character list and natural language translations from the encoded descriptions are automatically generated and formatted for display on the Web.

Developer of the DELTA software: M. J. Dallwitz, T. Paine and E. Zurcher

ICTVdB and DELTA related References


Comments to ICTVdB Management
Last updated on 25 April 2006 by Cornelia Büchen-Osmond
Copyright © 2002    International Committee on Taxonomy of Viruses.    All rights reserved.



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