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00.001.0.01.001. Human adenovirus C

Cite this publication as: ICTVdB Management (2006). 00.001.0.01.001. Human adenovirus C. In: ICTVdB - The Universal Virus Database, version 4. Büchen-Osmond, C. (Ed), Columbia University, New York, USA

Cite this site as: ICTVdB - The Universal Virus Database, version 4. http://www.ncbi.nlm.nih.gov/ICTVdb/ICTVdB/

Table of Contents

Classification

This is a description of a vertebrate virus at the species level.

ICTVdB Virus Code: 00.001.0.01.001. Virus accession number: 01001001. Obsolete virus code: 01.0.1.0.001; superceded accession number: 01010001.
NCBI Taxon Identifier NCBI Taxonomy ID: 129951.

Name, Synonyms and Lineage

ICTV approved acronym: HAdV-C. Virus is the type of the genus 00.001.0.01. Mastadenovirus in the family 00.001. Adenoviridae.

Virion Properties

Morphology

Virions consist of a capsid and a core. Virus capsid is not enveloped, round with icosahedral symmetry. The isometric capsid has a diameter of 70-90 nm. Capsids appear hexagonal in outline. The capsid surface structure reveals a regular pattern with distinctive features. The capsomer arrangement is clearly visible. The capsid consists of 252 capsomers. Surface projections are often lost during preparation, or distinct filaments protrude from the 12 vertices.

Capsids all have the same appearance, or can be penetrated by stain and some appear dark in the center; virus may occur together with a dependent virus.

Electron micrograph of human adenovirus courtesy of Dr Cornelia Büchen-Osmond taken at the Hygiene Institute, Medical Faculty, J-W-Goethe University, Frankfurt a. Main, Germany. Specimen stained with 3% PTA. Bar = 100 nm.


























Electron micrograph of human adenovirus courtesy of Dr Cornelia Büchen-Osmond taken at the Hygiene Institute, Medical Faculty, J-W-Goethe University, Frankfurt a. Main, Germany. Specimen stained with 3% PTA. Bar = 100 nm.

Nucleic Acid

The genome is not segmented and contains a single molecule of linear double-stranded DNA. The complete genome is 35937 nucleotides long. The NCBI reference genome has the accession number [NC_001405]. The genome has terminally redundant sequences. The terminally redundant sequences have inverted terminal repetitions (ITR). The 3'-terminus has conserved nucleotide sequences of 103 nucleotides in length.

GenBank records for nucleotide sequences; complete genome sequences.

Proteins

The viral genome encodes structural proteins and non-structural proteins.

Non-Structural Proteins: The virus codes for an DNA-dependent DNA polymerase. In addition to the polymerase, the virus codes for enzymes such as replicase.

Lipids

Lipids are not reported.

Transcription: Virus transcription is temporally regulated. The viral genome is transcribed by host cell enzymes.

During the early stage, the viral genome is transcribed by eukaryotic nuclear RNA polymerase II; late stage, the viral genome is transcribed by eukaryotic nuclear RNA polymerase III.

Translation: Virions may provide helper functions to dependent virus during replication. Virion acts as helper for a satellite virus.

Diagnostics and Reference Collections

Antisera are commercially available from American Type Culture Collection.

Biological Properties

Natural Host

Virus infects during its life cycle a single type of vertebrate host.
Domain
Viral hosts belong to the Domain Eucarya.

Domain Eucarya
Kingdom Animalia.

Kingdom Animalia
Phylum Chordata.

Phylum Vertebrata Class Mammalia.

Class Mammalia Order Primates, or Carnivora, or Artiodactyla;
Family Hominidae.

Data Sources and Contributions

The description has been compiled from data in the ICTV Report presented by Russell WC, Adrian T, Bartha A, Fujinaga K, Ginsberg HS, Hierholzer JC, de Jong JC, Li QG, Mautner V, Nasz I, Wadell G.

References

ICTV Report.

PubMed References.

Contributor

Data have been submitted online to ICTVdB on March 2005 by Yarina Hynd;
email: ICTVdB Management.

Taxonomic Proposals and Changes

A taxonomic proposal has been submitted to the ICTV by the Vertebrate Virus Subcommittee, Study Group for Adenoviridae at the meeting in San Diego, March 1998, to change the position of the taxon. The proposal has been approved by postal ballot following discussions at the meeting of the Executive Committee in San Diego, 1998, the taxon has been designated as Type Species (of the Genus Mastadenovirus).

Images

Taxon images: • EM by Cornelia Büchen-Osmond.



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DELTA - DEscription Language for TAxonomy developed by Dr Mike Dallwitz, Toni Paine and Eric Zurcher, CSIRO Entomology, Canberra, Australia. ICTVdB - The Universal Virus Database, developed for the International Committee on Taxonomy of Viruses by Dr Cornelia Büchen-Osmond is written in DELTA. The virus descriptions in ICTVdB are coded by, or using data from experts in the field of virology or members ICTV. The character list is the underlying code. All virus descriptions are based on the character list and natural language translations are automatically generated and formatted for display on the Web from the descriptions in DELTA-format. The description has been generated automatically from DELTA files. DELTA - DEscription Language for TAxonomy developed by Dr Mike Dallwitz, Toni Paine and Eric Zurcher, CSIRO Entomology, Canberra, Australia.

ICTVdB - The Universal Virus Database, developed for the International Committee on Taxonomy of Viruses (ICTV) by Dr Cornelia Büchen-Osmond, is written in DELTA. The virus descriptions in ICTVdB are coded by ICTV members and experts, or by the ICTVdB Management using data provided by the experts, the literature or the latest ICTV Report. The character list is the underlying code. All virus descriptions are based on the character list and natural language translations from the encoded descriptions are automatically generated and formatted for display on the Web.

Developer of the DELTA software: M. J. Dallwitz, T. Paine and E. Zurcher

ICTVdB and DELTA related References

Comments to ICTVdB Management
Last updated on 25 April 2006 by Cornelia Büchen-Osmond
Copyright © 2002    International Committee on Taxonomy of Viruses.    All rights reserved.


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